Alzheimer and Dementia News - Alz Research & Therapy

Dementia prevention: current epidemiological evidence and future perspective
published on February 12th, 2012 at 06:00 PM
Dementia, a major cause of disability and institutionalization in older people, poses a serious threat to public health and to the social and economic development of modern society. Alzheimer's ...
Lipidomics of Alzheimer's disease: Current status.
published on January 31st, 2012 at 06:00 PM
Alzheimer's disease (AD) is a cognitive disorder with a number of complex neuropathologies, including, but not limited to, neurofibrillary tangles, neuritic plaques, neuronal shrinkage, ...
Progranulin axis and recent developments in frontotemporal lobar degeneration
published on January 22nd, 2012 at 06:00 PM
Frontotemporal lobar degeneration (FTLD) is a devastating neurodegenerative disease that is the second most common form of dementia affecting individuals under age 65. The most common pathological ...
Statins and Therapy of Alzheimer's disease: Questions of Efficacy versus Trial Design
published on January 15th, 2012 at 06:00 PM
Recent trials of statins produced no benefit for subjects with Alzheimer's disease. These negative studies add to a growing list of negative clinical trials. These data point to a need for ...
Resting state functional MRI in Alzheimer's Disease
published on January 9th, 2012 at 06:00 PM
Resting-state functional magnetic resonance imaging (fMRI) is emerging as an interesting biomarker for measuring connectivity of the brain in patients with Alzheimer's disease (AD). In this review, ...
Vascular risk factors and Alzheimer's disease: are these risk factors for plaques and tangles or for concomitant vascular pathology that increases the likelihood of dementia? An evidence-based review
published on January 3rd, 2012 at 06:00 PM
Recent epidemiologic studies have noted that risk factors for atherosclerosis (for example, diabetes mellitus, hypertension, and hyperlipidemia) are associated with increased risk of incident ...
Beyond Amyloid: A diverse portfolio of novel drug discovery programs for Alzheimer's disease and related dementias: Meeting report from the 12th International Conference on Alzheimer's Drug Discovery, 26th-27th September 2011, Jersey City, NJ, USA.
published on December 19th, 2011 at 06:00 PM
Although the molecular mechanisms underlying the pathogenesis of Alzheimer's disease and other related neurodegenerative diseases remain unclear, accumulation of misfolded proteins, ...